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Inferior Vena Cava Agenesia and a Massive Bilateral Iliofemoral Venous Thrombosis

Department of Emergency Medicine, University, Department of Medicine, "Sestre Milosrdnice" University Hospital, Vinogradska Cesta 29, Zagreb, Croatia, zeljko.vucicevic{at}zg.t-com.hr

Vesna Degoricija, MD, PhD

Department of Emergency Medicine, University, Department of Medicine, "Sestre Milosrdnice" University Hospital, Vinogradska Cesta 29, Zagreb, Croatia

Zrinka Alfirevic, MD

Department of Emergency Medicine, University, Department of Medicine, "Sestre Milosrdnice" University Hospital, Vinogradska Cesta 29, Zagreb, Croatia

Mirella Sharma, MD

Department of Emergency Medicine, University, Department of Medicine, "Sestre Milosrdnice" University Hospital, Vinogradska Cesta 29, Zagreb, Croatia

The absence of the inferior vena cava is a rare congenital anomaly and represents a modest risk for deep-venous thrombosis. When associated with genetic polymorphism or other hypercoagulable states, the risk can increase several times. A case of young man with the inferior vena cava agenesia and deep-venous thrombosis of both legs triggered by the physical effort is reported. The view that the congenital inferior vena cava malformation represents a predisposition to deep-venous thrombosis in spite of well-developed collateral circulation is supported. In these circumstances, various external triggers (physical effort, hormonal contraception etc) may precipitate thrombosis. Because the patient had no other convincing and permanent risk factors for thrombosis, the lifelong anticoagulant therapy was not recommended.

Key Words: inferior vena cava agenesia • deep-venous thrombosis

This version was published on August 1, 2008

Angiology, Vol. 59, No. 4, 510-513 (2008)
DOI: 10.1177/0003319707305350


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