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Statins and Heart Failure
Theodosios D. Filippatos, MD
and
Dimitri P. Mikhailidis, MD, FACB, ASA, FFPM, FRCP, FRCPath*
Royal Free Hospital
* To whom correspondence should be addressed. E-mail: Mikhailidis{at}aol.com.
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Abstract |
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Retrospective studies show that statin use prevents congestive heart failure and decreases mortality in patients with congestive heart failure; however, only one prospective study is available. In the Controlled Rosuvastatin Multinational Trial in Heart Failure study, rosuvastatin (10 mg/d) was compared with placebo in patients with advanced coronary heart disease–related congestive heart failure. There was no significant difference between rosuvastatin and placebo except for hospitalization rates. Statins must be given to all patients with coronary heart disease as early as possible because they may not work in patients with advanced congestive heart failure.
First published on May 28, 2008, doi:10.1177/0003319708319643
Angiology 2008;59:58S.
A more recent version of this article appeared on August 1, 2008

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