|
Sign In to gain access to subscriptions and/or personal tools.
|
The Contrast Media Iohexol Causes Vasoconstriction of the Proximal Left Anterior Descending Coronary Artery: Implications for Appropriate Stent Sizing
Robert V. Kelly,
Michael J. Gillespie,
Mauricio G. Cohen,
David P. McLaughlin,
E. Magnus Ohman,
and
George A. Stouffer*
* To whom correspondence should be addressed. E-mail: rstouff{at}med.unc.edu.
 |
Abstract |
|---|
The effect of the contrast agent iohexol on reference vessel size in patients with proximal left anterior descending disease is unknown. Quantitative coronary angiography and intravascular ultrasound were performed in 15 patients with atherosclerotic disease of the proximal left anterior descending. Mean proximal reference vessel diameter was 2.95 ± 0.59 mm with quantitative coronary angiography and 4.65 ± 0.66 mm with intravascular ultrasound (P < .05). Intracoronary injection of iohexol resulted in a significant decrease in intravascular ultrasound-measured proximal reference vessel diameter from 4.65 ± 0.66 mm to 4.47 ± 0.68 mm (P = .002). Vasoconstrictive response to iohexol in the proximal reference vessel ranged from -0.04 mm to 0.5 mm with a mean of 0.18 ± 0.16 mm. This study shows that iohexol can cause significant vasoconstriction of the proximal reference vessel in patients with severe disease involving the proximal left anterior descending.
First published on May 27, 2008, doi:10.1177/0003319708318375
Angiology 2008;59:574.
A more recent version of this article appeared on October 1, 2008
 CiteULike  Complore  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter What's this?
|
|
