|
Sign In to gain access to subscriptions and/or personal tools.
|
Effect of Antihypertensive Therapy on Serum Lipids in Newly Diagnosed Essential Hypertensive Men
Hanumanthappa Nandeesha,
Purushothaman Pavithran*,
and
T Madanmohan
* To whom correspondence should be addressed. E-mail: pavithranpp{at}gmail.com.
 |
Abstract |
|---|
The effect of antihypertensives on serum lipids in newly diagnosed male essential hypertensive patients was studied. The participants (n = 99) were randomly allocated to receive amlodipine, atenolol, enalapril, hydrochlorothiazide, and a combination of amlodipine and atenolol. Lipid parameters were estimated before and after 8 weeks of therapy. The atenolol and thiazide group showed a significant increase in triglycerides (TGs) and verylow-density lipoprotein cholesterol (VLDL-C). High-density lipoprotein cholesterol (HDL-C) and HDL-C to low-density lipoprotein cholesterol (LDL-C) ratio were significantly increased and TC to HDL-C ratio was significantly decreased in the amlodipine and amlodipine– atenolol combination groups. In the enalapril group, we found a significant reduction in TC, TGs, VLDL-C, non-HDL-C, and TG to HDL-C ratio after treatment. It can be concluded from the present study that some drugs have beneficial effects on the lipid status, whereas others adversely affect the lipid status in hypertension.
First published on April 29, 2008, doi:10.1177/0003319708316167
Angiology 2009;60:217.
A more recent version of this article appeared on April 1, 2009
 CiteULike  Complore  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter What's this?
|
|
