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Augmentation Index and Pulse Wave Velocity as Indicators of Cardiovascular Stiffness
Ichiro Nakae, MD*,
Shinro Matsuo, MD,
Tetsuya Matsumoto, MD,
Kenichi Mitsunami, MD,
and
Minoru Horie, MD
Shiga University of Medical Science
* To whom correspondence should be addressed. E-mail: nakae{at}belle.shiga-med.ac.jp.
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Abstract |
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The authors examine the clinical significance of radial augmentation index (rAI) and brachial-ankle pulse wave velocity (baPWV). In 78 hypertensive patients, rAI correlates inversely with pulse rate (PR; r = -0.57, P <.001), but baPWV does not. A weak correlation between rAI and systolic blood pressure (SBP) is observed (r = 0.28, P < .05). rAI has no significant correlation with diastolic blood pressure (DBP). In contrast, baPWV correlates positively with both SBP (r = 0.54, P<.001) and DBP (r = 0.43, P lt;.001). In 56 of these patients, baPWV correlates with the diastolic parameters—the mitral E/A ratio (r = –0.35, P <.01), pulmonary vein S/D ratio (r = 0.41, P < .01), and deceleration time (r = 0.28, P < .05)—by echocardiography, but AI.P75 (rAI corrected for PR 75 bpm because of PR dependence) does not. Therefore, for detection of diastolic dysfunction, baPWV may be more sensitive than rAI.
First published on April 2, 2008, doi:10.1177/0003319707306299
Angiology 2008;59:421.
A more recent version of this article appeared on August 1, 2008

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