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Angiology
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Article

Hierarchical Analysis of Cardiovascular Risk Factors in Relation to the Development of Acute Coronary Syndromes, in Different Parts of Greece: The CARDIO2000 Study

Demosthenes B. Panagiotakos, PhD*, Christos Pitsavos, MD, PhD, Christine Chrysohoou, MD, PhD, and Christodoulos Stefanadis, MD, PhD

Harokopio University

* To whom correspondence should be addressed. E-mail: dbpanag{at}hua.gr.


   Abstract
During 2000 to 2002, 700 men (59 ±10 years) and 148 women (65 ±9 years) patients with first event of an ACS were randomly selected from cardiology clinics of Greek regions. Afterwards, 1078 population-based, age-matched and sex-matched controls were randomly selected from the same hospitals. The frequency ratio between men and women in the case series of patients was about 4:1, in both south and north Greek areas. Hierarchical classification analysis showed that for north Greek areas family history of coronary heart disease, hypercholesterolemia, hypertension, diabetes (explained variability 35%), and less significantly, dietary habits, smoking, body mass index, and physical activity status (explained variability 4%) were associated with the development of ACS, whereas for south Greek areas hypercholesterolemia, family history of coronary heart disease, diabetes, smoking, hypertension, dietary habits, physical activity (explained variability 34%), and less significantly body mass index (explained variability <1%), were associated with the development of the disease.

First published on April 2, 2008, doi:10.1177/0003319707304576

Angiology 2008;59:156.

A more recent version of this article appeared on May 1, 2008


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