This Article Full Text (OnlineFirst PDF) All Versions of this Article: 0003319707303835v1 59/3/379    most recent Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Yamashita, K. Articles by Tasaki, H. Search for Related Content PubMed PubMed Citation Articles by Yamashita, K. Articles by Tasaki, H. Social Bookmarking                         What's this?

Intracoronary Administration of Isosorbide Dinitrate Induced Severely Slow Flow and Transient ST-Segment Elevation

University of Occupational and Environmental Health School of Medicine

^* To whom correspondence should be addressed. E-mail: wajinn{at}med.uoeh-u.ac.jp.

	Abstract

Nitroglycerin is one of the most widely used drugs in the treatment of angina. However, nitroglycerin fails to relieve angina in patients with syndrome X who have microvessel dysfunction. Microvessel function is impaired in several diseases. In this article, the authors report that despite normal coronary angiograms at control, intracoronary administration of isosorbide dinitrate induced severe coronary slow flow and transient ST-segment elevation with mild chest pain in a patient with congestive heart failure. The authors speculated that functional stenosis and a delay in the dilatation of microvessels less than 100 µm in diameter because of their dysfunction resulted in a severely slow flow after intracoronary administration of isosorbide dinitrate.

First published on April 2, 2008, doi:10.1177/0003319707303835

Angiology 2008;59:379.

A more recent version of this article appeared on July 1, 2008


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?