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Angiology
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Article

The Use of Positron Emission Tomography With (18)F-Fluorodeoxyglucose for the Diagnosis of Vascular Graft Infection

Patrick Lauwers, MD, Sylvie Van den Broeck, MD, Laurens Carp, MD, Jeroen Hendriks, PhD, Paul Van Schil, PhD*, and Pierre Blockx, PhD

* To whom correspondence should be addressed. E-mail: paul.van.schil{at}uza.be.


  Abstract
Vascular graft infection is associated with a high morbidity and mortality rate. Diagnosis is difficult, as there is no single diagnostic criterion that has a 100% accuracy. A combination of physical examination, laboratory tests, and several imaging techniques is mandatory. Beside a wide range of indications in the oncological field, positron emission tomography with (18)F-fluorodeoxyglucose (FDG-PET) has a well-known role in the diagnosis of bone and soft-tissue infections. Some authors have recently reported on the potential use of FDG-PET in the diagnosis of vascular graft infections. The aim of this study is to review personal experience. Five consecutive patients with a suspected prosthetic infection (1 aortobifemoral bypass, 3 femoropopliteal bypasses, and 1 femorofemoral bypass) underwent FDG-PET. All prostheses showed a moderate or intense FDG tracer uptake. All 3 patients with an intense FDG uptake proved to have a prosthetic infection (based on microbiologic examination). These preliminary results suggest that FDG-PET might be an interesting tool to confirm vascular graft infection.

First published on December 10, 2007, doi:10.1177/0003319707299205

Angiology 2008;58:717.

A more recent version of this article appeared on January 1, 2008

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