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Angiology
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0003319706292010v1
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*Coronary Artery Disease
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Article

Relation of Serum Uric Acid Levels With the Presence and Severity of Angiographic Coronary Artery Disease

Mustafa Gur MD*, Remzi Yilmaz MD, Recep Demirbag MD, and Nurten Aksoy MD

* To whom correspondence should be addressed. E-mail: drmugur{at}yahoo.com.


  Abstract
The aim of this study is to investigate the association between uric acid level and severity of coronary artery disease. Consecutive 495 patients with coronary artery disease and 356 individuals with normal coronary angiograms were included in the study. Severity of coronary artery disease was evaluated using the Gensini score index. For both groups, conventional risk factors, the levels of uric acid, and other biochemical markers were assessed. The mean uric acid levels of the patient group were significantly higher than those of the control group (P = .002). Mean uric acid levels were higher in men than in women (P < .001). In the coronary artery disease group, there was no significant correlation between uric acid levels and Gensini score in both sexes. Thus, it can be concluded that uric acid level is associated with the presence but not with the severity of coronary artery disease.

First published on April 2, 2008, doi:10.1177/0003319706292010

Angiology 2008;59:166.

A more recent version of this article appeared on May 1, 2008

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