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Vascular Remodeling After Carotid Artery Stenting

Dipartimento di Medicina Clinica e Sperimentale

C. Piergentili, MD

Dipartimento di Medicina Clinica e Sperimentale

M. Zanardo, MD

Dipartimento di Medicina Clinica e Sperimentale

R. Rocchi, MD

Dipartimento di Medicina Clinica e Sperimentale

M. Giordan, MD

Cardiologia, Università di Padova

P. Cardaioli, MD

Cardiologia, Università di Padova

P. Pauletto, MD

Dipartimento di Medicina Clinica e Sperimentale, Medicina I Azienda Ospedaliera di Treviso, Italy

Carotid stenting is an alternative to endarterectomy for the treatment of carotid stenosis. To determine the role of vascular remodeling after stent placement, we studied 19 high surgical risk patients undergoing carotid stenting for severe stenosis. Using high-resolution ultrasound, we evaluated the intima-media thickness (IMT), the intima-intima diameter, and the adventitia-adventitia diameter at prespecified sites of the carotid artery tree during 3 years of follow-up. The IMT of internal carotid artery, at the site of maximum stenosis, increased significantly from 0 mm after 24 hours, to 0.41 mm at 3 months, to 0.48 mm at 6 months, and to 0.51 mm at 3 years of follow-up. In the same site, diameters and residual stenosis (range 29-24%) did not change over time. Our study showed that stent is self-expanding against the atherosclerotic plaque within the 3-year follow-up period. Despite neointima formation, the intima-intima diameter does not change without worsening of the residual stenosis.

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Angiology, Vol. 58, No. 5, 565-571 (2007)
DOI: 10.1177/0003319706294611


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This Article Abstract Free Full Text (Free PDF) Free Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in Web of Science Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Web of Science (1) Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Puato, M. Articles by Pauletto, P. Search for Related Content PubMed PubMed Citation Articles by Puato, M. Articles by Pauletto, P. Social Bookmarking                         What's this?