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Mortality After First Myocardial Infarction in Greek Patients: A 4-Year Follow-Up Study

First Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece, genovefa{at}kolovou.com

Constantinos Mihas, MD, MSc

First Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece

Anastasia Kotanidou

Internal Medicine Department, General Hospital of Kimi, Kimi, Greece (Constantinos M); Medical School, University of Athens, Athens, Greece

Yvoni Dimoula

First Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece

Georgia Karkouli

Department of Nursing, Technical School of Education, Athens, Greece (YD, Christina M); "Atticon" General Hospital, Athens, Greece

Olga Kadda

First Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece

Katherine Anagnostopoulou, BSc, MSc

First Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece

Dimitri P. Mikhailidis, MD, FRCP

Department of Clinical Biochemistry (Vascular Prevention Clinics), Royal Free Hospital campus, University College Medical School, University College London, London, United Kingdom

Christina Marvaki, RN, PhD

First Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece

Background: Death associated with coronary heart disease (CHD) depends in part on the time since the myocardial infarction (MI) and modification of risk factors. Methods: This observational, retrospective 4-year follow-up study consisted of 804 patients (628 men). The participants completed a questionnaire reporting diet, demographic factors, personal behavior (smoking, physical activity), anthropometry, prior medical conditions (hypertension, diabetes mellitus), and recent medication. Results: During 48 months of follow-up, 12% of men and 15% of women died. Older age, longer duration of smoking, and frequency of exercise were significantly different between survivors and the deceased (P = .014, P = .014, P = .001, respectively). Multivariate analysis revealed associations with years of smoking (odds ratio, OR: 1.10, P = .025), treatment with nitrates (OR: 4.81, P = .024), and increased frequency of exercise (OR: 0.42, P = .013), adjusting for age and gender. Conclusions: We should emphasize cessation of smoking and increased physical activity in MI survivors. Antismoking programs should start at an early age.

Key Words: coronary heart disease • mortality • observational-retrospective study • myocardial infarction

This version was published on October 1, 2009

Angiology, Vol. 60, No. 5, 582-587 (2009)
DOI: 10.1177/0003319709343285


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