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Angio-Seal Use in Patients with Peripheral Arterial Disease (ASPIRE)

Department of Angiology, Hanusch Hospital, Vienna, Austria, Reinhold.katzenschlager{at}wgkk.sozvers.at

Reinhold Tischler, MD

Department of Radiology, Hanusch Hospital, Vienna, Austria

Georg Kalchhauser, MD

Department of Radiology Hanusch Hospital, Vienna, Austria

Michael Panny, MD

Department of Angiology, Hanusch Hospital, Vienna, Austria

Mirko Hirschl, MD

Department of Angiology, Hanusch Hospital, Vienna, Austria

Purpose: To investigate the incidence of complications after the use of an arterial closure device (Angio-Seal) in patients with peripheral arterial disease. Methods: In 105 consecutive patients after transfemoral catheterization, the puncture site was closed using a closure device (Angio-Seal). Colour-flow-duplexsonography studies were conducted 1 to 4 days before, within 3 days after and 3 month after the intervention. Results: All patients had peripheral arterial disease, 34 had calcification at the puncture site. Detection of calcification did not prevent device deployment. Complications (2 minor bleedings, 1 pseudoaneurysm) were not associated with high risk groups (these were: 69 antegrade punctures, 22 obese and 32 hypertensive patients). Three-month postinterventional diameter and blood velocity changes were <1%. Conclusions: Patients with peripheral arterial disease in the region of the puncture site and patients at higher complication risk can safely and effectively be closed with an Angio-Seal device. At the puncture site, no lumen change can be observed 3 months postinterventional.

Key Words: peripheral arterial disease • closure device • complications • angiography • angioplasty

This version was published on October 1, 2009

Angiology, Vol. 60, No. 5, 536-538 (2009)
DOI: 10.1177/0003319708330007


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