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Screening for Deep Vein Thrombosis in Asymptomatic High-risk Patients: A Comparison Between Digital Photoplethysmography and Venous Ultrasonography

Cardiovascular Department, National Research Institute of Tuberculosis and Lung Disease (NRITLD), Shaheed Beheshti University of Medical Sciences & Health Services, Tehran, Iran

Neda Behzadnia, MD

Cardiovascular Department, National Research Institute of Tuberculosis and Lung Disease (NRITLD), Shaheed Beheshti University of Medical Sciences & Health Services, Tehran, Iranp-shahabi{at}nritld.ac.ir

Payman Shahabi, MD

Cardiovascular Department, National Research Institute of Tuberculosis and Lung Disease (NRITLD), Shaheed Beheshti University of Medical Sciences & Health Services, Tehran, Iran,

Makan Sadr, MD

Cardiovascular Department, National Research Institute of Tuberculosis and Lung Disease (NRITLD), Shaheed Beheshti University of Medical Sciences & Health Services, Tehran, Iran

Objective: To determine the role of digital photoplethysmography in screening asymptomatic patients who are susceptible for developing deep vein thrombosis.

Methods: Three hundred and thirty-seven limbs in 169 patients who were high risk for development of deep vein thrombosis were assessed by ultrasonography digital photoplethysmography and the results were compared.

Results: Thirteen limbs were found to have deep vein thrombosis as demonstrated by ultrasonography. All limbs with a venous refilling time greater than 12 seconds had a normal ultrasonography. Compared with

ultrasonography and using refilling time less than 12 seconds as the cutoff point, digital photoplethysmography achieved a sensitivity, specificity, positive predictive value, and negative predictive value of 100%, 73.8%, 13.3%, and 100% respectively, for detecting deep vein thrombosis in asymptomatic high-risk patients.

Conclusion: Digital photoplethysmography is a simple, noninvasive, and highly sensitive test for screening of deep vein thrombosis.

Key Words: deep vein thrombosis (DVT) • digital photoplethysmography (D-PPG) • screening • diagnosis

This version was published on June 1, 2009

Angiology, Vol. 60, No. 3, 301-307 (2009)
DOI: 10.1177/0003319708323494


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