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Predictors of Long-Term Major Adverse Cardiac Events and Clinical Restenosis Following Elective Percutaneous Coronary Stenting

Department of Internal Medicine, Geisinger Medical Center, Danville, Pennsylvania

Kimberly Skelding, MD

Department of Cardiology, Geisinger Medical Center, Danville, Pennsylvania, kaskelding{at}geisinger.edu

Arthur Armstrong, Jr, MD, PhD

Department of Internal Medicine, Geisinger Medical Center, Danville, Pennsylvania

Dipan Desai, DO

Department of Internal Medicine, Geisinger Medical Center, Danville, Pennsylvania

G. Craig Wood, MS

Geisinger Center for Research, Geisinger Medical Center, Danville, Pennsylvania

James Blankenship, MD

Department of Cardiology, Geisinger Medical Center, Danville, Pennsylvania

Limited data exist regarding the predictors of long-term clinical outcomes following elective percutaneous coronary intervention (PCI) in the current era of stenting. The authors investigated the predictors of major adverse cardiac events (MACE) and clinical restenosis in 740 consecutive patients who underwent successful elective PCI with bare metal stents (BMSs) or drug-eluting stents (DESs). At 30-month follow-up, compared with BMS recipients, DES recipients had a significantly lower rate of MACE, which was mainly driven by a decreased repeat target vessel PCI. The rate of 30-month clinical restenosis was significantly lower in DES recipients. The authors conclude that baseline clinical, angiographic, and procedural characteristics determine long-term MACE and clinical restenosis after elective PCI, with DES being the independent predictor for both.

Key Words: percutaneous coronary intervention • stents • coronary artery disease

This version was published on April 1, 2009

Angiology, Vol. 60, No. 2, 141-147 (2009)
DOI: 10.1177/0003319708321587


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