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Carotid and Femoral Atherosclerosis in Chronic Hepatitis C: A 5-Year Follow-Up

Department of Medical and Surgical Science, Clinica Medica , Università di Padova, franca.bilora{at}sanita.padova.it

Enrico Campagnolo, MD

Department of Medical and Surgical Science, Clinica Medica , Università di Padova

Roberto Rinaldi, MD

Divisione di Malattie Infettive, Azienda Ospedaliera di Padova Padova, Italy

Alberto Rossato, MD

Department of Medical and Surgical Science, Clinica Medica , Università di Padova

Marianna Arzenton, MD

Department of Medical and Surgical Science, Clinica Medica , Università di Padova

Francesco Petrobelli, MD

Department of Medical and Surgical Science, Clinica Medica , Università di Padova

The objective of this study was to assess the progression of atherosclerosis in carotid and femoral arteries after a 5-year period using ultrasound in subjects with chronic hepatitis C and in controls matched for classic atherosclerotic risk factors. A total of 40 patients and 40 controls were assessed by echocolor Doppler in 2001 and in 2006 to evaluate plaque and intima-media thickness. The patients showed no changes in plaque and intima-media thickness during the 5-year period in all districts examined, whereas a significant increase in intima-media thickness in the carotid sections was recorded in the controls. Chronic hepatitis C seems to cause delay in the atherosclerotic process.

Key Words: chronic C hepatitis • atherosclerosis • intima-media thickness • ultrasound

This version was published on January 1, 2009

Angiology, Vol. 59, No. 6, 717-720 (2009)
DOI: 10.1177/0003319707311536


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