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This version was published on July 1, 2008
Angiology, Vol. 59, No. 3, 278-282 (2008)
DOI: 10.1177/0003319708316898

Does Gender Influence the Patency of Infrainguinal Bypass Grafts?

Ufuk Alpagut, MD

Department of Cardiovascular Surgery, Istanbul University Istanbul Medical Faculty, Istanbul, Turkey

Murat Ugurlucan, MD

Department of Cardiovascular Surgery, Istanbul University Istanbul Medical Faculty, Istanbul, Turkey, muratugurlucan{at}yahoo.com

Maciej Banach, MD, PhD, FASA, MAHA

Department of Cardiology, 1st Chair of Cardiology and Cardiac Surgery, Lodz University Medical Faculty, Lodz, Poland

Dimitri P. Mikhailidis, MD, FRCPath

Department of Clinical Biochemistry (Vascular Disease Prevention Clinics), Royal Free University College School of Medicine, University College London, London, UK

Enver Dayioglu, MD

Department of Cardiovascular Surgery, Istanbul University Istanbul Medical Faculty, Istanbul, Turkey

Infrainguinal revascularization is an effective method of treatment for femoropopliteal/tibial occlusive diseases. However, these bypass grafts are prone to stenosis. In this retrospective study, the authors investigate the association of gender with patency of infrainguinal bypass grafts. The outcomes for consecutive 375 male and 200 female patients who underwent infrainguinal bypass surgery for arterial occlusive disease are compared, and associations with characteristics of the patients, surgical procedure, and graft stenosis are determined. It is found that several demographic, biochemical, and etiological factors could influence the patency of bypass procedures in different genders. However, infrainguinal arterial reconstruction procedures performed in women have a worse outcome when compared with that in men.

Key Words: infrainguinal bypass • gender • patency • distal bypass • occlusive disease • reconstruction


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