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Prevalence of Metabolic Syndrome in Patients With Clinically Advanced Peripheral Vascular Disease

Department of Medicine-Endocrinology, Kuwait University, lailaqadan{at}hotmail.com

Adel A. Ahmed, MD

Department of Radiology

Hussein A. Safar, MD

Department of Surgery, Mubarak Al-kabeer Hospital, Ministry of Health

Marzouk A. Al-Bader, MD

Department of Surgery, Mubarak Al-kabeer Hospital, Ministry of Health

Amr A. Ali, MD

Department of Radiology Mubarak Al-Kabeer Hospital, Ministry of Health, Kuwait

The aim of this cross-sectional study was to determine the prevalence of metabolic syndrome (MetS) and its components among 100 patients with progressive peripheral arterial disease (PAD) referred for diagnostic angiography in preparation for a revascularization procedure. The prevalence of MetS was more than 95%. Diabetes mellitus was the most prevalent component followed by hypertension and low high-density lipoprotein. Almost half the patients aggregated in the highest metabolic score category. A direct relationship was identified between the number of MetS components and serum uric acid (P = .001) and C-reactive protein (P = .826), whereas an inverse relationship was seen between the clustering of components and androgen levels in men (P < .001). For PAD, which could have a benign clinical course, early screening for MetS might identify those at greater risk of failing conservative therapy and progressing to a more aggressive atherosclerotic disease typically associated with high morbidity and mortality.

Key Words: peripheral vascular disease • peripheral arterial disease • metabolic syndrome • critical leg ischemia

This version was published on May 1, 2008

Angiology, Vol. 59, No. 2, 198-202 (2008)
DOI: 10.1177/0003319707304582


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