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Angiology
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*Brain Aneurysm
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Ruptured Cerebral Aneurysm and Acute Coronary Artery Dissection in the Setting of Multivascular Fibromuscular Dysplasia

A Case Report

Sergey V. Brodsky, MD, PhD

Department of Pathology, New York Medical College and Westchester Medical Center, Valhalla, NY, sergey_brodsky{at}nymc.edu

Gita Ramaswamy, MD

Department of Pathology, New York Medical College and Westchester Medical Center, Valhalla, NY

Praveen Chander, MD

Department of Pathology, New York Medical College and Westchester Medical Center, Valhalla, NY

Alex Braun, MD

Department of Pathology, New York Medical College and Westchester Medical Center, Valhalla, NY

Fibromuscular dysplasia (FMD) is a segmental noninflammatory nonatherosclerotic vascular disease that has been described in almost every arterial bed, including the cerebral and coronary arteries. FMD of cerebral vessels has been associated with development of saccular aneurysms in the involved vessels. Acute dissection of coronary arteries is also a rare complication of FMD. Herein, we report the first case of both complications of FMD occurring in a single patient—a ruptured anterior communicating artery aneurysm and a right coronary artery dissection occurring in a 38-year-old woman. At autopsy, FMD was found in multiple vascular beds. Our findings reveal the potential for involvement of several vascular beds in patients with FMD, resulting in multiple vascular complications.

Angiology, Vol. 58, No. 6, 764-767 (2008)
DOI: 10.1177/0003319707303645
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