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Angiology, Vol. 58, No. 1S, 27S-35S (2007)
DOI: 10.1177/0003319706297741
© 2007 SAGE Publications

Efficacy and Tolerability of Liposomal Heparin Spraygel as an Add-on Treatment in the Management of Superficial Venous Thrombosis

Reinhold Katzenschlager

Department of Angiology, Hanuschkrankenhaus, Vienna, Austria, Reinhold.katzenschlager{at}wgkk.sozvers.at

Ara Ugurlouglu

Department of Vascular Surgery, LKH, Salzburg, Austria

Gyula Sipos

Department of Angiology, BAZ Country Hospital, Miskolc, Hungary

Imre Bihari

Department of Cardiovascular Surgery, Szabolcs, Budapest, Hungary

Eva B. Anyova

Institute of Surgery, Military Medical Institute, Warszawa, Poland

Mirko Hirschl

Department of Angiology, Hanuschkrankenhaus, Vienna, Austria

Marek Maruszynski

Ambulance of Vascular Surgery, Kapiszoryho, Nove Zamky, Slovakia

Wojciech Noszczyk

Clin. General Surgery, Medical School, Warzawa, Poland

Zbigniew Rybak

Ars-Medica, Private Clinic, Wroclaw, Poland

Andrzej Cencora

Department of Vascular Surgery, Hosp. St. Grandego, Krakow, Poland

Superficial venous thrombosis usually resolves spontaneously in a few weeks. In most cases, treatment includes peroral analgesics or nonsteroidal anti-inflammatory drugs accompanied by the recommendation to wear elastic stockings and perform regular mild ambulation. In contrast to this "standard treatment," a recent ACCP guideline has recommended that patients affected by spontaneous superficial thrombophlebitis be treated with intermediate doses of unfractionated or low-molecular-weight heparin. This study was designed to assess the efficacy of topically applied heparin spraygel in terms of reduction of local symptoms and signs of superficial venous thrombosis.


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