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Noninvasive Tissue Characterization of Coronary Arterial Plaque by 16-Slice Computed Tomography in Acute Coronary Syndrome

First Department of Integrated Medicine, Omiya Medical Center, Jichi Medical School, Saitama, Japan

Takanori Yasu, MD

First Department of Integrated Medicine, Omiya Medical Center, Jichi Medical School, Saitama, Japan, tyasu{at}omiya.jichi.ac.jp

Yasuyuki Kobayashi, MD

First Department of Integrated Medicine, Omiya Medical Center, Jichi Medical School, Saitama, Japan

Takuji Katayama, MD

First Department of Integrated Medicine, Omiya Medical Center, Jichi Medical School, Saitama, Japan

Yoshitaka Sugawara, MD

First Department of Integrated Medicine, Omiya Medical Center, Jichi Medical School, Saitama, Japan

Hiroshi Funayama, MD

First Department of Integrated Medicine, Omiya Medical Center, Jichi Medical School, Saitama, Japan

Yousuke Takagi, MD

First Department of Integrated Medicine, Omiya Medical Center, Jichi Medical School, Saitama, Japan

Nahoko Ikeda, MD

First Department of Integrated Medicine, Omiya Medical Center, Jichi Medical School, Saitama, Japan

Takeshi Ishida, MD

First Department of Integrated Medicine, Omiya Medical Center, Jichi Medical School, Saitama, Japan

Yoshio Tsuruya, MD

First Department of Integrated Medicine, Omiya Medical Center, Jichi Medical School, Saitama, Japan

Norifumi Kubo, MD

First Department of Integrated Medicine, Omiya Medical Center, Jichi Medical School, Saitama, Japan

Muneyasu Saito, MD

First Department of Integrated Medicine, Omiya Medical Center, Jichi Medical School, Saitama, Japan

Noninvasive characterization of coronary plaques is challenging for cardiologists. The authors’ goal was to explore the clinical feasibility of newly developed 16-slice computed tomography (CT) in tissue characterization of coronary arterial plaques in patients with acute coronary syndrome. Sixteen patients with acute coronary syndrome underwent 16-slice CT (Aquillion, Toshiba) and coronary arteriography with intravascular ultrasound (IVUS) within 7 days. Twenty-three plaques were classified by IVUS according to plaque echogenicity: 6 soft plaques, 11 intermediate plaques, and 6 calcified plaques. Mean (±SD) CT numbers (Hounsfield units [HU]) of these 3 types of plaques were 50.6 ±14.8 HU, 131 ±21.0 HU, and 721 ±231 HU, respectively. Sixteen-slice CT facilitates noninvasive tissue characterization of coronary arterial plaques.

Angiology, Vol. 57, No. 2, 155-160 (2006)
DOI: 10.1177/000331970605700204


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