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Three-Dimensional Gadolinium-Enhanced Magnetic Resonance Angiography Used as a "One-stop Shop" Imaging Procedure for Venous Thromboembolism: A Pilot Study

Department of Internal Medicine, and Magnetic Resonance Institute, Divisions of Angiology and Nuclear Medicine, Karl-Franzens University Hospital, Graz, Austria, andrea.obernosterer{at}uni-graz.at

Manuela Aschauer, MD

Department of Radiology, Divisions of Angiology and Nuclear Medicine, Karl-Franzens University Hospital, Graz, Austria

Horst Portugaller, MD

Department of Radiology, Divisions of Angiology and Nuclear Medicine, Karl-Franzens University Hospital, Graz, Austria

Herwig Köppel, MD

Department of Internal Medicine, and Magnetic Resonance Institute, Divisions of Angiology and Nuclear Medicine, Karl-Franzens University Hospital, Graz, Austria

Rainer W. Lipp, MD

Department of Internal Medicine, and Magnetic Resonance Institute, Divisions of Angiology and Nuclear Medicine, Karl-Franzens University Hospital, Graz, Austria

Pulmonary embolism and deep venous thrombosis are individual manifestations of a single entity, venous thromboembolic disease. This study aimed to assess the feasibility of 3-dimensional gadolinium-enhanced magnetic resonance angiography used as an "one-stop shop" imaging procedure visualizing both the pulmonary arteries and the deep lower venous system within a single investigation. The inclusion criterion was a proven or excluded venous thromboembolism. Diagnosis was based on an imaging work-up for pulmonary embolism including either perfusion lung scan or contrast-enhanced spiral computed tomography, or both, and an imaging work-up for deep venous thrombosis including either venous color-coded duplex sonography or ascending phlebography, or both. A gadolinium-enhanced "one-stop shop" magnetic resonance angiography was performed within 24 hours of completed diagnostic imaging work-up for pulmonary embolism and deep venous thrombosis in 20 patients. Results of pulmonary magnetic resonance angiography were concordant with perfusion lung scan and/or computed tomography in 90% of patients. Magnetic resonance angiography results of the deep lower venous system were concordant with venous duplex sonography and/or phlebography in 75% of patients and seemed to be more precise in 25% of patients. The "one-stop shop" imaging procedure using gadolinium-enhanced magnetic resonance angiography was feasible and proved to offer a reliable and rapid diagnostic approach in thromboembolic disease, sparing patients’ exposure to ionizing radiation and iodinated contrast media.

Angiology, Vol. 56, No. 4, 423-430 (2005)
DOI: 10.1177/000331970505600410


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