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Impaired Left Ventricle Filling in Slow Coronary Flow Phenomenon: An Echo-Doppler Study

Department of Cardiology, Faculty of Medicine, Inonu University, Malatya, Turkey, alpayt.sezgin{at}superonline.com

Ergun Topal, MD

Department of Cardiology, Faculty of Medicine, Inonu University, Malatya, Turkey

Irfan Barutcu, MD

Department of Cardiology, Faculty of Medicine, Inonu University, Malatya, Turkey

Ramazan Ozdemir, MD

Department of Cardiology, Faculty of Medicine, Inonu University, Malatya, Turkey

Hakan Gullu, MD

Department of Cardiology, Faculty of Medicine, Inonu University, Malatya, Turkey

Emrah Bariskaner, MD

Department of Cardiology, Faculty of Medicine, Inonu University, Malatya, Turkey

Necip Ermis, MD

Department of Cardiology, Faculty of Medicine, Inonu University, Malatya, Turkey

Izzet Tandogan, MD

Department of Cardiology, Faculty of Medicine, Inonu University, Malatya, Turkey

Nusret Acikgoz, MD

Department of Cardiology, Faculty of Medicine, Inonu University, Malatya, Turkey

Nasr Sivri, MD

Department of Cardiology, Faculty of Medicine, Inonu University, Malatya, Turkey

Slow coronary flow (SCF) in a normal-appearing coronary angiogram is a well-recognized clinical entity, but its etiopathogenesis remains unclear. The aim of the study was to evaluate echocardiographic features in patients with SCF. Thirty-four patients with angiographically proven SCF (group I) and 25 patients with normal coronary flow (group II) were enrolled in the study. The diagnosis of SCF was made with use of the "TIMI frame count (TFC)" method. All patients underwent complete transthoracic echocardiographic examination (M-mode, 2-dimensional [2-D], and Doppler parameters such as color, continuous, pulsed wave). There were no significant differences with respect to systolic parameters between the 2 groups; in spite of these, group I showed impaired left ventricular diastolic patterns compared to group II. Group I patients had higher peak late diastolic filling velocities due to enhanced atrial systole (A), lower peak (E/A) diastolic filling velocity ratios, and longer isovolumetric relaxation times compared with group II, and these were statistically significant (p<0.001). In conclusion; the authors detected diastolic filling abnormalities and showed diastolic dysfunction in patients with SCF.

Angiology, Vol. 56, No. 4, 397-401 (2005)
DOI: 10.1177/000331970505600406


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