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Angiology, Vol. 55, No. 1, 93-97 (2004)
DOI: 10.1177/000331970405500114

Capecitabine-Induced Coronary Vasospasm

A Case Report

Asad A. Rizvi, MD

Divisions of Cardiology, Department of Medicine, Hartford Hospital, Hartford, CT.

Peter Schauer, MD

Divisions of Hematology/Oncology, Department of Medicine, Hartford Hospital, Hartford, CT.

Dariush Owlia, MD

Divisions of Cardiology, Department of Medicine, Hartford Hospital, Hartford, CT.

James E. Kallal, MD

Divisions of Cardiology, Department of Medicine, Hartford Hospital, Hartford, CT.

The authors report the case of a 70-year-old man with metastatic colon cancer and no known history of coronary disease or major risk factors who developed coronary vasospasm after the initiation of capecitabine (Xeloda®). Although coronary vasospasm has been associated with another older fluoropyrimidine compound, 5-fluorouracil, this is the first reported occurrence with this relatively newer cancer drug.


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