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Angiology
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Comparison of Changes in Diastolic Functions After Aortic Valve Replacement with Freestyle Stentless Porcine Xenografts in Patients with Restrictive and Nonrestrictive Physiology

Mustafa Özcan Soylu, MD

Department of Cardiology, Türkiye Yüksek Ihtisas Hospital, Ankara, Turkey.

Ahmet Duran Demir, MD

Department of Cardiology, Türkiye Yüksek Ihtisas Hospital, Ankara, Turkey.

Özcan Özdemir, MD

Department of Cardiology, Türkiye Yüksek Ihtisas Hospital, Ankara, Turkey.

Yücel Uzun, MD

Department of Cardiology, Türkiye Yüksek Ihtisas Hospital, Ankara, Turkey.

Aysegül Kunt, MD

Department of Cardiology, Türkiye Yüksek Ihtisas Hospital, Ankara, Turkey.

Sule Korkmaz, MD

Department of Cardiology, Türkiye Yüksek Ihtisas Hospital, Ankara, Turkey.

Oguz Tasdemir, MD

Department of Cardiovascular Surgery, Türkiye Yüksek Ihtisas Hospital, Ankara, Turkey.

In this study, the effect of valve replacement on diastolic parameters was evaluated preop eratively and postoperatively at 3, 6, and 12 months by comparing diastolic parameters in patients after aortic valve replacement with freestyle stentless porcine xenografts for aortic stenosis. Depending on deceleration time (DT) and isovolumetric relaxation time (IVRT) with preoperative echocardiographic assessment, patients were divided into two groups: restrictive physiology (DT ≤ 150 msec and IVRT < 100 msec, 20 patients), and nonrestrictive physiology (DT > 150 msec and IVRT ≥ 100 msec, 27 patients). Although left ventricular mass index signif icantly decreased in both groups, improvement in DT, IVRT, and ejection fraction occurred only in patients with restrictive physiology. As a result, the patients with restrictive diastolic characteristics had more benefit than the patients with nonrestrictive physiology after aortic valve replacement.

Angiology, Vol. 54, No. 6, 655-659 (2003)
DOI: 10.1177/000331970305400604
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