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Criteria Predictive of Limb Viability at 1 Year in Patients with Chronic Severe Ischemia-TcPO 2 and Demographic Parameters

D. Eveno, MD

S. Le Lamer, MD

M. Ledemeney, MD

C. Haon

D. Chomard, MD

Centre la Fontaine au Bac 53170-Le Bignon du Maine France

Following an earlier study, the investigators sought to identify and define objective prog nostic criteria of viability at 1 year of a limb with severe chronic ischemia. A study was undertaken in 116 patients (118 limbs) (74 men and 42 women), with a mean age of 71.9 years for men and 81.6 years for women. Static transcutaneous oxygen pressure (TcPO ₂) was measured with a verticalization sensitization test and inhalation of oxygen on JO and viability of the limb noted 1 year later. Logistic analysis was made of 13 oximetry parameters and two demographic parameters (age and gender). Results were analyzed in absolute terms and by tissue oxygenation ratio (TOR) (ratio between absolute TcPO₂ at the foot and at a chest reference electrode). Six factors appeared to be prog nostic factors of limb viability at 1 year, statistically significant at 6% according to threshold values: age, verticalization TcPO₂, TcPO₂ after 1 minute's inhalation of oxygen, TcPO₂ after 4 minutes' inhalation of oxygen, and slope of TcPO ₂ and slope of TOR between 1 and 4 minutes' inhalation. A 1 year viability index integrating these criteria is suggested.

Angiology, Vol. 51, No. 9, 765-776 (2000)
DOI: 10.1177/000331970005100909


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