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Angiology
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Ticlopidine-Induced Severe Agranulocytosis After the Placement of Coronary Artery Stent

A Case Report

Ramazan Sari, MD

Inonu University, School of Medicine Department of Internal Medicine Turgut Ozal Medical Center 44300 Malatya Turkey

Alper Sevinc, MD

Suleyman Buyukberber, MD

Ticlopidine is an oral antiplatelet agent frequently utilized in the treatment of cere brovascular disease. It is rarely associated with severe bone marrow suppression. A case of an elderly woman is reported who developed febrile agranulocytosis two months after commencing ticlopidine but who had a favorable outcome after cessation of that drug and treatment with granulocyte colony-stimulating factor (G-CSF). All patients should have regular monitoring of their blood counts during therapy with ticlopidine.

Angiology, Vol. 51, No. 7, 591-593 (2000)
DOI: 10.1177/000331970005100707
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