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Angiology, Vol. 51, No. 4, 281-288 (2000)
DOI: 10.1177/000331970005100402

Percutaneous Transluminal Coronary Angioplasty Performed 24-48 Hours After the Onset of Acute Myocardial Infarction Improves Chronic-Phase Left Ventricular Regional Wall Motion

Takayuki Nakabayashi, MD

Takahiro Hayashi, MD

Yoshikazu Inoue, MD

Akiko Ikeda, MD

Hideki Morii, MD

Norikatsu Naito, MD

Kinji Ishikawa, MD

Ken Kanamasa, MD

First Department of Internal Medicine Kinki University School of Medicine Ohno-Higashi 377-2 Osakasayama, Osaka 589-8511 Japan

The authors investigated the capacity of percutaneous transluminal coronary angioplasty (PTCA) performed 24-48 hours after the onset of acute myocardial infarction (AMI) to improve regional left ventricular wall motion. Twenty-four patients were divided into two groups: a PTCA group who received successful PTCA (14 cases) and a non-PTCA group (10 cases) who did not receive PTCA. Left ventricular end-diastolic volume (LVEDV) increased significantly (p < 0.01) from 57 ±14 mL/m 2 during the acute phase to 83 ± 16 mL/m2 during the chronic phase in the non-PTCA group, whereas no signifi cant change in LVEDV was seen in the PTCA group (69 ±26 vs 76 ±16 mL/m2). In addition, in patients with 99% stenosis/thrombolysis in myocardial infarction (TIMI) grade 3 flow, increases in regional left ventricular wall motion ({Delta}sd/chord) at the infarcted site between the acute and chronic phases were significantly greater in the PTCA group than in the non-PTCA group (2.49 ± 1.05 vs 0.67 ±0.65, p <0.01). PTCA performed 24-48 hours after the onset of AMI improved wall motion at the infarcted site.


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