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Evaluation of Electron Beam Tomographic Coronary Arteriography with Three-Dimensional Reconstruction in Healthy Subjects

Department of Radiology, FuWai Cardiovascular Institute and Hospital, Peking Union Medical College, and Chinese Academy of Medical Sciences, Beijing, China.

RuPing Dai, MD

Department of Radiology, FuWai Cardiovascular Institute and Hospital, Peking Union Medical College, and Chinese Academy of Medical Sciences, Beijing, China.

Hua Bai, BS

Department of Radiology, FuWai Cardiovascular Institute and Hospital, Peking Union Medical College, and Chinese Academy of Medical Sciences, Beijing, China.

Sha He, MS

Department of Radiology, FuWai Cardiovascular Institute and Hospital, Peking Union Medical College, and Chinese Academy of Medical Sciences, Beijing, China.

BaoLian Jing, MD

Department of Radiology, FuWai Cardiovascular Institute and Hospital, Peking Union Medical College, and Chinese Academy of Medical Sciences, Beijing, China.

Nan Zhuang, MD

Department of Radiology, FuWai Cardiovascular Institute and Hospital, Peking Union Medical College, and Chinese Academy of Medical Sciences, Beijing, China.

RunLin Gao, MD

Department of Internal Medicine, Division of Cardiology, FuWai Cardiovascular Institute and Hospital, Peking Union Medical College, and Chinese Academy of Medical Sciences, Beijing, China.

YueJin Yang, MD

Department of Internal Medicine, Division of Cardiology, FuWai Cardiovascular Institute and Hospital, Peking Union Medical College, and Chinese Academy of Medical Sciences, Beijing, China.

JiLin Chen, MD

Department of Internal Medicine, Division of Cardiology, FuWai Cardiovascular Institute and Hospital, Peking Union Medical College, and Chinese Academy of Medical Sciences, Beijing, China.

Matthew J. Budoff, MD

Division of Cardiology, Harbor-UCLA Research and Education Institute, Torrance, California.

In this study, the authors evaluated the performance characteristics of contrast-enhanced electron-beam tomography (EBT) with three-dimensional reconstruction in defining the coronary artery lumen in healthy subjects. Thirty patients with normal coronary angiograms by selective coronary arteriography (SCA) underwent contrast-enhanced EBT examination. Measured parameters included degree of luminal enhancement, intravascular contrast-to-noise ratio (CNR), and diameter and length of visualized lumen. Ventricular cavity, aortic blood pool, and coronary artery attenuation were found to be significantly different before and after intravenous injection of contrast material (p < 0.001). CNR decreased from proximal to distal segments within each vessel (p < 0.001), with a peak of 11.2 ±2.3 occurring in the proximal left anterior descending coronary artery (LAD) to a low of 4.8 2.0 in the distal left circumflex (LCX). Luminal diameters visualized by EBT had no significant difference with that of SCA (p > 0.05). Therefore, EBT angiography with three-dimensional reconstruction allows for noninva sive coronary arteriography revealing long segments of the major coronary arteries in normal subjects.

Angiology, Vol. 51, No. 11, 895-904 (2000)
DOI: 10.1177/000331970005101102


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