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Acute Reversible Cardiomyopathy and Thromboembolism After Cisplatin and 5-Fluorouracil Chemotherapy

A Case Report

Hemalatha Vasireddy, MD

Anita Kuruvilla, MD

Boris Gambarin, MD

Majesh Makan, MD

Barry I. Saul, MD, FACA

Division of Cardiology New York Methodist Hospital 506, 6th Street Brooklyn, NY 11215

Acute development of cardiomyopathy and occlusive thromboembolic events following cisplatin and 5-fluorouracil (5-FU) is rare but frequently lethal. The authors report the successful management of such an event in a 52-year-old man with squamous cell carcinoma of the soft palate. The possible pathophysiological mechanisms are discussed.

Angiology, Vol. 51, No. 10, 873-878 (2000)
DOI: 10.1177/000331970005101011


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