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Catastrophic Arterial Reactivity During Primary Antiphospholipid Syndrome

A Case Report

B. Granel, MD

P. Morange, MD

P. Piquet, MD

J. Serratrice, MD

C. de Roux, MD

I. Juhan-Vague, MD

P.J. Weiller, MD

Patrick Disdier, MD

Service de Médecine Interne du professeur P. J. Weiller Hôpital de la Timone Boulevard Jean Moulin 13385 Marseille Cedex 5 France

Arterial reactivity leading to acute thrombosis at the site of a needle stick injury has never been described during antiphospholipid syndrome. The authors report a case char acterized by a succession of thrombotic events occurring during or immediately after arterial angiographies or arterial surgery, in which catastrophic arterial reactivity can be strongly suspected. In this particular patient, it can be postulated that damage to the endothelial cells of the vessels injured during manipulation may have precipitated or aggravated the preexisting susceptibility to thrombosis.

Angiology, Vol. 50, No. 9, 761-764 (1999)
DOI: 10.1177/000331979905000910


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