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Medial Arterial Calcification Is Frequently Found in Patients with Microalbuminuria

Venetsana Kyriazopoulou, MD

Apostolos G. Vagenakis, MD

Apostolos G. Vagenakis, MD

University of Patras Medical School Patras Greece 26500

The presence of medial arterial calcification (MAC), often referred to as Moncheberg's sclerosis, was sought in patients with long-standing diabetes mellitus. One hundred patients aged 22-50 years were initially divided into two groups, those with neuropathy and those without. As expected, the incidence of MAC was significantly higher in the neuropathy group (40% vs 20%) . When the patients were divided into two groups, those with MAC and those without, it appeared that the incidence of MAC was very high in patients who had microalbuminuria (57% vs 13%) and particularly when microalbuminuria was combined with neuropathy (40% vs 7%). It is concluded that microalbuminuria is a strong predicting factor of medial arterial sclerosis independent of neuropathy.

Angiology, Vol. 50, No. 12, 971-975 (1999)
DOI: 10.1177/000331979905001202


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