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Angiology
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Successful Treatment of Ergotism with Iloprost

A Case Report

R. Piquemal, MD

Service de medecine interne B, hôpital Bretonneau, Tours Cedex; and the Service de medecine vasculaire et Centre Claude Bernard de Recherche sur les maladies vasculaires, hôpital Broussais, Paris Cedex, France.

J. Emmerich, MD, PhD

Service de medecine vasculaire et Centre Claude Bernard de Recherche sur les maladies vasculaires, hôpital Broussais, Paris Cedex, France.

J.L. Guilmot, MD, PhD

Service de medecine interne B, hôpital Bretonneau, Tours Cedex; and the Service de medecine vasculaire et Centre Claude Bernard de Recherche sur les maladies vasculaires, hôpital Broussais, Paris Cedex, France.

J.N. Fiessinger, MD, PhD

Service de medecine vasculaire et Centre Claude Bernard de Recherche sur les maladies vasculaires, hôpital Broussais, Paris Cedex, France.

A 34-year-old woman was hospitalized for severe acute arterial insufficiency of the limbs. Overuse of ergotamine derivative was acknowledged by the patient, who had a long history of migraine headaches. An arteriogram showed diffuse arterial spasm and occlusion of right leg distal arteries. Intravenous infusion of a stable prostacyclin analog (Iloprost) was administered. Rapid and complete improvement of arteriospasm was noted within a few hours, confirmed by a further arteriogram. This appears to be one of the rare case reports of successful limb salvage by use of Iloprost for ergotism.

Angiology, Vol. 49, No. 6, 493-497 (1998)
DOI: 10.1177/000331979804900612
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