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Ventricular Arrhythmias in Normotensive Subjects and in Mild Hypertensive Patients

Department of Internal Medicine, Spedali Civili, Brescia, Italy.

Massimo Crippa, MD

Department of Internal Medicine, Spedali Civili, Brescia, Italy.

Gianpaolo Damiani, MD

Department of Internal Medicine, Spedali Civili, Brescia, Italy.

Ilaria Notaristefano, MD

Department of Internal Medicine, Spedali Civili, Brescia, Italy.

Raffaella Costa, MD

Department of Internal Medicine, Spedali Civili, Brescia, Italy.

Enrico Boni, MD

Department of Internal Medicine, Spedali Civili, Brescia, Italy.

Luciano Corda, MD

Department of Internal Medicine, Spedali Civili, Brescia, Italy.

Ermanna Chiari, MD

Department of Internal Medicine, Spedali Civili, Brescia, Italy.

Augusto Zaninelli, MD

Department of Internal Medicine, Spedali Civili, Brescia, Italy.

Twenty-five normotensive subjects (14 men, 11 women) aged from 25 to 60 years (mean 36) and 30 untreated patients with mild hypertension (stages 1 and 2, JNC V) without target organ damage (16 men, 14 women), aged 26-59 years (mean 35.8) underwent continuous 24-hour ECG Holter monitoring with a Fukuda Denshi SM-40 ambulatory recorder and SCM-400 ECG analyzer. During 24-hour ambulatory ECG recording, mean heart rate was slightly but not significantly higher in hypertensive patients (73.3 ± 10 beats per minute [bpm]) in comparison with normotensive subjects (71.2 ± 12 bpm). The prevalence of premature atrial contractions was similar in the two groups. Total ventricular arrhythmias were more prevalent in the group of mild hypertensive patients (P<0.05), who also had a higher prevalence in complex forms of ectopy (r=0.81 for bigeminy; r=0.83 for trigeminy; r=0.83 for couplets). Holter recordings did not show abnormalities of ST-T wave or episodes of silent ischemia.

Angiology, Vol. 49, No. 2, 99-103 (1998)
DOI: 10.1177/000331979804900202


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