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Beneficial Hemodynamic Effects of Oral Prostacyclin (PGI2) Analogue, Beraprost Sodium, on a Patient with Primary Pulmonary Hypertension

A Case Report

Second Department of Internal Medicine, Ehime University School of Medicine, Shigenobu-cho, Onsen-gun, Ehime 791-02, Japan.

Mareomi Hamada, MD, FACA

Second Department of Internal Medicine, Ehime University School of Medicine, Shigenobu-cho, Onsen-gun, Ehime 791-02, Japan.

Yuji Shigematsu, MD

Second Department of Internal Medicine, Ehime University School of Medicine, Shigenobu-cho, Onsen-gun, Ehime 791-02, Japan.

Shuntaro Ikeda, MD

Second Department of Internal Medicine, Ehime University School of Medicine, Shigenobu-cho, Onsen-gun, Ehime 791-02, Japan.

Taishi Kuwahara, MD

Second Department of Internal Medicine, Ehime University School of Medicine, Shigenobu-cho, Onsen-gun, Ehime 791-02, Japan.

Hideo Kawakami, MD

Second Department of Internal Medicine, Ehime University School of Medicine, Shigenobu-cho, Onsen-gun, Ehime 791-02, Japan.

Yuji Hara, MD

Second Department of Internal Medicine, Ehime University School of Medicine, Shigenobu-cho, Onsen-gun, Ehime 791-02, Japan.

Koji Kodama, MD

Second Department of Internal Medicine, Ehime University School of Medicine, Shigenobu-cho, Onsen-gun, Ehime 791-02, Japan.

Katsuhiko Kohara, MD

Second Department of Internal Medicine, Ehime University School of Medicine, Shigenobu-cho, Onsen-gun, Ehime 791-02, Japan.

Kunio Hiwada, MD, FACA

Second Department of Internal Medicine, Ehime University School of Medicine, Shigenobu-cho, Onsen-gun, Ehime 791-02, Japan.

A 65-year-old woman was admitted to our hospital because of exertional dyspnea in 1987. A diagnosis of primary pulmonary hypertension was confirmed by right heart catheterization. She had received conventional therapy in the outpatient clinic. She was readmitted with the deterioration of exertional dyspnea in 1995. Stabilization of pulmonary hemodynamics, while not achieved with conventional therapy, was achieved with additive administration of an oral prostacyclin (PGI₂) analogue, beraprost sodium.

Angiology, Vol. 49, No. 2, 161-164 (1998)
DOI: 10.1177/000331979804900210


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