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Successful Treatment of Intermittent Claudication Due to Spinal Canal Stenosis Using Beraprost Sodium, a Stable Prostaglandin I2 Analogue

A Case Report

Department of Internal Medicine, Saga Medical School, Saga 849, Japan

Sei Emura, MD, PhD

Department of Internal Medicine, Saga Medical School, Saga 849, Japan

Kiyoko Ngashima, MD

Department of Internal Medicine, Saga Medical School, Saga 849, Japan

Hayato Kishikawa, MD, PhD

Department of Internal Medicine, Saga Medical School, Saga 849, Japan

Toshinobu Takashima, MD, PhD

Department of Internal Medicine, Saga Medical School, Saga 849, Japan

Keizo Ohmori, MD, PhD

Department of Internal Medicine, Saga Medical School, Saga 849, Japan

The syndrome of intermittent claudication can be induced not only by vascular insuffi ciency of the lower limbs but also by diseases of the spinal cord and cauda equina. The authors describe a sixty-year-old man with intermittent claudication due to spinal canal stenosis who was successfully treated with beraprost sodium, a stable prostaglandin I₂ analogue. This drug has a long biological half-life and is orally effective in vasodilation, which is suggested to be beneficial in treating this syndrome. Beraprost sodium may become one of the major drugs for conservative therapy of intermittent claudication induced by spinal canal stenosis.

Angiology, Vol. 48, No. 5, 457-461 (1997)
DOI: 10.1177/000331979704800510


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