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Aortic Dissection in a Patient Receiving Chemotherapy for Hodgkin's Disease

A Case Report

David J. Vaughn, MD

Gary W. Crooks, MD

George A. Holland, MD

Joseph E. Bavaria, MD

Michael A. Golden, MD

The Hospital of the University of Pennsylvania 3400 Spruce Street Philadelphia, PA 19104

Cancer chemotherapy is associated with a wide range of vascular toxicities, which may be related to endothelial cell damage by these agents. The authors describe a patient with Hodgkin's disease who developed an atypical aortic dissection while receiving MOPP/ABV chemotherapy (nitrogen mustard, vincristine, procarbazine, prednisone, doxorubicin, bleomycin, and vinblastine). They would place aortic dissection on the list of potential vascular complications associated with antineoplastic agents.

Angiology, Vol. 48, No. 12, 1063-1065 (1997)
DOI: 10.1177/000331979704801207


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