This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Wada, T. Articles by Yamazaki, S. Search for Related Content PubMed PubMed Citation Articles by Wada, T. Articles by Yamazaki, S. Social Bookmarking                         What's this?

Common Carotid Artery Wall Properties in Takayasu's Arteritis

Department of Preventive Medicine, The Jikei University School of Medicine, Tokyo, Japan

Kuniyasu Kodaira

Department of Internal Medicine (4), The Jikei University School of Medicine, Tokyo, Japan

Kentaro Fujishiro

Department of Internal Medicine (4), The Jikei University School of Medicine, Tokyo, Japan

Ken-ichi Maie

Department of Internal Medicine (4), The Jikei University School of Medicine, Tokyo, Japan

Eiji Tsukiyama

Department of Internal Medicine (4), The Jikei University School of Medicine, Tokyo, Japan

Tsutomu Fukumoto

Department of Internal Medicine (4), The Jikei University School of Medicine, Tokyo, Japan

Tomoko Uchida

Department of Internal Medicine (4), The Jikei University School of Medicine, Tokyo, Japan

Sayaka Yamazaki

Department of Internal Medicine (4), The Jikei University School of Medicine, Tokyo, Japan

The vessel wall properties of the common carotid artery have been noninvasively and quantitatively assessed with an ultrasonic instrument. Stiffness parameter β, which repre sents the mechanical properties of the vessel, was calculated from the relationship between blood pressure and the diameter of the artery. There are no reports that quan titatively assess wall properties in Takayasu's arteritis.

The authors compared, in vivo, the vessel wall properties of the common carotid artery in 14 patients with Takayasu's arteritis versus those in 60 normal subjects (controls). They measured changes in the inner diameter of the artery between systole and diastole with an ultrasonic, phase-locked, echo-tracking system. β was significantly higher in Takayasu's arteritis than in normal subjects (better than a 99% confidence interval). The findings for each decade were as follows: 3rd decade (20s): 35.7 ±28.9 vs 5.01-6.46, P=0.0001; 4th decade (30s): 19.5 ±9.71 vs 6.09-7.80, P=0.02; 5th decade (40s): 26.2 ±11.3 vs 7.26-9.28, P=0.0001; 6th decade (50s): 19.1 ±4.27 vs 8.66-11.25, P=0.0001.

Takayasu's arteritis significantly impaired the mechanical performance of the common carotid artery. Thus, β shows promise as a useful diagnostic indicator of Takayasu's arteritis.

Angiology, Vol. 47, No. 7, 669-674 (1996)
DOI: 10.1177/000331979604700705


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?