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Multiple Cholesterol Emboli Syndrome—Six Cases Identified Through the Spontaneous Reporting System

Medical Department, Sterling Winthrop Inc., New York, New York

Judith Norwich

Medical Department, Sterling Winthrop Inc., New York, New York

Elizabeth Shapiro

Medical Department, Sterling Winthrop Inc., New York, New York

Lester Reich

Medical Department, Sterling Winthrop Inc., New York, New York

Kasia uljaga Petchel

Medical Department, Sterling Winthrop Inc., New York, New York

David Goldsmith

Medical Department, Sterling Winthrop Inc., New York, New York

Six cases of suspected multiple cholesterol emboli syndrome were identified by a review of reports contained in the company's records of adverse event reports. Antecedent risk factors in these reports included cardiac catheterization, thrombolytic therapy, translumbar aortography, renal arteriography, subclavian arteriography, abdominal aortography, and heparinization. Unlike the commonly reported subacute presentation, onset occurred during or immediately after catheterization in 5 of the 6 patients reported. Acute renal failure; hypertension; back, leg, and/or abdominal pain; and livedo reticularis were the events most frequently reported. Angiographers should consider multiple choles terol embolization when multiple organ system dysfunction occurs during or immedi ately after intraarterial catheterization.

Angiology, Vol. 46, No. 9, 779-784 (1995)
DOI: 10.1177/000331979504600903


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