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Angiology
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Inferior Vena Caval Thrombosis Associated with Acute Pancreatitis: An Unusual Vascular Complication—Its Presentation and Management

Suresh J. Antony, M.D., M.R.C.P.

Department of Medicine, East Carolina University School of Medicine, Greenville, North Carolina

Terri Loomis, M.D.

Department of Medicine, East Carolina University School of Medicine, Greenville, North Carolina

Lisa Brumble, M.D.

Department of Medicine, East Carolina University School of Medicine, Greenville, North Carolina

Mark D. Hannis, M.D.

Department of Medicine, East Carolina University School of Medicine, Greenville, North Carolina

Vascular thrombosis and systemic hypercoagulable states are known complications of acute pancreatitis. They are thought to be secondary to the release of proteolytic enzymes of the pancreas. Inferior vena caval thrombosis is an extremely rare complication of chronic pancreatitis and has, to the authors' knowledge, never been reported in acute pancreatitis.

The clinical presentation and radiographic findings are reviewed to illustrate the disease spectrum. Early treatment with intravenous heparin appears to be an effective therapy. Familiarity with this complication will aid physicians in its early diagnosis. However, a high degree of suspicion for this complication is necessary to make a diagnosis.

Angiology, Vol. 45, No. 12, 1009-1014 (1994)
DOI: 10.1177/000331979404501203


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