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Angiology
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Brain Hemorrhage in Mixed Connective Tissue Disease

A Case Report

Kazunori Toyoda

Department of Internal Medicine, Kitakyushu City Wakamatsu Hospital, Kitakyushu City, Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka City

Hiroshi Tsuji

Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka City

Seizo Sadoshima

Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka City

Choji Horimoto

Department of Neurosurgery, Kitakyushu City Yahata Hospital, Kitakyushu City, Japan

Masatoshi Fujishima

Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka City

Mixed connective tissue disease (MCTD) uncommonly develops stroke, although collagen disease is an important condition for stroke. A nonhypertensive woman with MCTD developed massive putaminal hemorrhage. No obvious predisposing factors were revealed by clinical and pathologic examination. MCTD may contribute to the develop ment of brain hemorrhage by some mechanism other than hypertension.

Angiology, Vol. 45, No. 11, 967-972 (1994)
DOI: 10.1177/000331979404501110
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