SAGE Journals Online
Advertisement
Sign In to gain access to subscriptions and/or personal tools.

 

Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Advertisement

Sign In to gain access to subscriptions and/or personal tools.
Angiology
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Santoian, E. C.
Right arrow Articles by Ramwell, P. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Santoian, E. C.
Right arrow Articles by Ramwell, P. W.
Right arrowPubmed/NCBI databases
*Compound via MeSH
*Substance via MeSH
Hazardous Substances DB
*HYDROXYLAMINE
*NITROGLYCERIN
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Vasodilator Effects of Hydroxylamine in the Isolated Rodent Lung

Edward C. Santoian

Department of Physiology and Biophysics, Georgetown University Medical Center, Washington, D.C.

George Thomas

Department of Physiology and Biophysics, Georgetown University Medical Center, Washington, D.C.

Allan D. Angerio

Department of Physiology and Biophysics, Georgetown University Medical Center, Washington, D.C.

Peter A. Kot

Department of Physiology and Biophysics, Georgetown University Medical Center, Washington, D.C.

Peter W. Ramwell

Department of Physiology and Biophysics, Georgetown University Medical Center, Washington, D.C.

Hydroxylamine is a natural product of cellular metabolism that possesses vasodilating properties similar to those of endothelium-derived relaxing factor (EDRF). In the rodent pulmonary circulation preconstricted with the endo peroxide analog U-46619, hydroxylamine relaxed the vasculature in a concen tration-dependent manner. Blockade of the hydroxylamine vasodilator response by methylene blue indicated that the mechanism of vasorelaxation is similar to that of EDRF. In this preparation, hydroxylamine is a more potent vasodilator than nitroglycerin.

Angiology, Vol. 44, No. 11, 897-901 (1993)
DOI: 10.1177/000331979304401108
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?




Advertisement