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Angiology
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Changes of Soft-Tissue Water Examined With Magnetic Resonance and Electrical Impedance Tomography: An in Vivo Experiment

K.W. Sievers

Department of Radiology, University of Essen

J. Gauger

Institute for Aerospace Medicine, DLR Cologne, Germany

T. Bauermann

Department of Radiology, University of Essen

E. Löhr

Department of Radiology, University of Essen

The purpose of this study was the examination of short-term changes in soft- tissue water under in vivo conditions. In 12 healthy volunteers the water distri bution of a selected slice of the lower limb was examined after change of position and rapid infusion of 0.9% saline solution. Two methods were used for data acquisition: magnetic resonance imaging (MRI) (Repetition Time (TR) = 1600 msec, Inverstion Time (TI) = 300 msec, Echo Time (TE) = 22 msec) and electrical impedance tomography (EIT). In orthostatic equilibrium all 12 volunteers dem onstrated changes of MR signal intensity and resistivity in the range of 12% and 7%, respectively. After infusion, mean changes of signal intensity and resistivity were 7% and 4%, respectively. The overall correlation of MRI and EIT was —0.96 (p < 0.001). Results indicate that inversion recovery sequences are a sen sitive method of detecting in vivo changes of water distribution in selected areas of the body.

Angiology, Vol. 44, No. 11, 889-895 (1993)
DOI: 10.1177/000331979304401107
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