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Blood Rheology After LDL Apheresis Using Dextran Sulfate Cellulose Absorption—A Case Report

Department of Internal Medicine, University of Ulm, Germany, Department of Physical Medicine and Rehabilitation University of Vienna, Vienna, Austria

Herwig H. M. Ditschuneit

Department of Internal Medicine, University of Ulm, Germany, Department of Physical Medicine and Rehabilitation University of Vienna, Vienna, Austria

Reinhard Hehr

Department of Internal Medicine, University of Ulm, Germany, Department of Physical Medicine and Rehabilitation University of Vienna, Vienna, Austria

R. Willi Grunewald

Department of Internal Medicine, University of Ulm, Germany, Department of Physical Medicine and Rehabilitation University of Vienna, Vienna, Austria

Edzard Ernst

Department of Internal Medicine, University of Ulm, Germany, Department of Physical Medicine and Rehabilitation University of Vienna, Vienna, Austria

Vinzenz Hombach

Department of Internal Medicine, University of Ulm, Germany, Department of Physical Medicine and Rehabilitation University of Vienna, Vienna, Austria

The authors describe a thirty-eight-year-old woman with familial hyper cholesterolemia treated by dextran sulfate cellulose adsorption apheresis. This technique and the selective extracorporeal LDL cholesterol elimination by im munoabsorption or heparin-induced precipitation not only dramatically decrease blood lipids but also result in a marked improvement in the rheologic profile. It is suggested that the amelioration of blood rheology by LDL apheresis may represent the cause for the early clinical improvement felt by most patients with severe coronary heart disease and hypercholesterolemia.

Angiology, Vol. 43, No. 7, 606-609 (1992)
DOI: 10.1177/000331979204300710


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