This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Caillard, P. Articles by Pr Cloarec, M. Search for Related Content PubMed PubMed Citation Articles by Caillard, P. Articles by Pr Cloarec, M. Social Bookmarking                         What's this?

Objectifying Exercise Ischemia in Peripheral Vascular Disease: A Study in 120 Patients

Outpatient Policlinic, The Tenon Hospital

Xavier Mouren

Outpatient Policlinic, The Tenon Hospital

Bertrand Pujade

Department of Vascular Surgery, The Tenon Hospital, Paris, France

Philippe Blanchemaison

Outpatient Policlinic, The Tenon Hospital

Yves Elbeze

Outpatient Policlinic, The Tenon Hospital

Maurice Pr Cloarec

Outpatient Policlinic, The Tenon Hospital

This study presents the results of transcutaneous oxygen pressure (TcPO₂) monitoring during a treadmill test walk performed in the early stages of peripheral obliterative vascular disease. The study population consisted of a first group of 50 known arteriopathic patients presenting, on questioning, with intermittent claudication; a second group of 50 known arteriopathic patients void of any symptoms of intermittent claudication; and a third group, which was a control cohort of 20 nonarteriopathic, nonclaudicating patients.

Though resting TcPO ₂ cannot be used to aid the clinical diagnosis of exercise ischemia it may be useful in revealing asymptomatic chronic resting ischemia (9% of cases in this series). On the other hand, a posteffort (recovery phase) fall in TcPO₂ had a predictive positive diagnostic accuracy for ischemia on exercise in 99% of the cases reported here versus 87% for clinical appraisal. In the light of these results, TcPO₂ measurements coupled to a treadmill test walk perfectly ascertain exercise ischemia in arteriopathic patients, whether asymptomatic or not, and avoid the false-positive results obtained by clinical evaluation.

Angiology, Vol. 41, No. 6, 469-478 (1990)
DOI: 10.1177/000331979004100608


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

This article has been cited by other articles:

				S. Qian and T. Iwai Intraoperative Evaluation of Success and Failure of Vascular Reconstruction by Monitoring the Transcutaneous Partial Pressure of Oxygen Vascular and Endovascular Surgery, September 1, 2000; 34(5): 483 - 490. [Abstract] [PDF]

				X. Mouren, P. Caillard, J.-J. Bensoussan, M. Massonneau, S. Gamand, and W. H. Stevens The effect of naftidrofuryl on transcutaneous oxygen tension during a treadmill test in patients with peripheral arterial occlusive disease Vascular Medicine, February 1, 1998; 3(1): 9 - 14. [Abstract] [PDF]

				X. Mouren, Ph. Caillard, M. Massonneau, and B. Thebault TcPO 2 Measurement Reproducibility During Stress in Stage II Obliterative Arterial Disease Angiology, April 1, 1996; 47(4): 329 - 336. [Abstract] [PDF]

				P. de Groote, A. Millaire, G. Deklunder, P. Marache, E. Decoulx, and G. Ducloux Comparative Diagnostic Value of Ankle-to-Brachial Index and Transcutaneous Oxygen Tension at Rest and After Exercise in Patients with Intermittent Claudication Angiology, February 1, 1995; 46(2): 115 - 122. [Abstract] [PDF]

				S. Qian, T. Iwai, Y. Inoue, and M. Endo A Comparative Analysis of Transcutaneous Oxygen Tension (tcPO2) During Rest and Postischemic Response Test in the Diagnosis of Patients with Mild and Moderate Arteriosclerosis Obliterans (ASO) Vascular and Endovascular Surgery, July 1, 1994; 28(6): 393 - 400. [Abstract] [PDF]

				X. Mouren, Ph. Caillard, and F. Schwartz Study of the Antiischemic Action of EGb 761 in the Treatment of Peripheral Arterial Occlusive Disease by TcPo2 Determination Angiology, June 1, 1994; 45(6): 413 - 417. [Abstract] [PDF]

				P. Caillard, X. Mouren, O. Bailliart, and M. Cloarec Evaluation of Ifenprodil Efficacy on Exercise-Induced Tissue Ischemia in Stage II Arteriopathy by Measurement of Transcutaneous Oxygen Tension During a Standard Treadmill Test: Double-Blind Study of Injectable Ifenprodil Versus Placebo Angiology, July 1, 1993; 44(7): 552 - 560. [Abstract] [PDF]