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Angiology
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Heparin-Induced Thrombocytopenia: A Case Report

H. Van Damme

Department of Thoracic and Cardiovascular Surgery, University Hospital Sart-Tilman

P. Damas

Department of Anaesthesiology, University Hospital Sart-Tilman

J.L. David

Thrombosis-Hemostasis Unit, University Hospital Sart-Tilman, Liège, Belgium

R. Limet

Department of Thoracic and Cardiovascular Surgery, University Hospital Sart-Tilman

The authors report a case of heparin-induced thrombocytopenia, in whom massive pulmonary embolism occurred in spite of heparin anticoagulation. Suc cessful pulmonary thrombectomy was carried out under cardiopulmonary by pass, with limitation of platelet clumping during bypass by aggregation inhibitors. This report is a comprehensive contribution to a better understanding of this rare immunoallergic complication of heparin administration, with a high incidence of serious thromboembolic events. The optimal management for cases of unavoid able reexposure to heparin is discussed.

Angiology, Vol. 41, No. 12, 1075-1081 (1990)
DOI: 10.1177/000331979004101209


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