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Angiology
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Quantitation of Anbornal 67GA Uptake in Pulmonary Interstitial Vascular Disease—A New Test to Detect Diffuse Lung Disease

Stephen L. Demeter

Northeastern Ohio Universities College of Medicine, Rootstown, Ohio

Edward M. Cordasco

Cleveland Clinic Foundation, Cleveland, Ohio

William MacIntyre

Cleveland Clinic Foundation, Cleveland, Ohio

James O'Donnell

Cleveland Clinic Foundation, Cleveland, Ohio

Joseph A. Golish

Cleveland Clinic Foundation, Cleveland, Ohio

D.H.I. Feiglin

Cleveland Clinic Foundation, Cleveland, Ohio

G.B. Saha

Cleveland Clinic Foundation, Cleveland, Ohio

Joseph Stepanitis

Cleveland Clinic Foundation, Cleveland, Ohio

Gallium 67 has been used as a modality to diagnose and follow the clinical course of diseases such as tumors, infections, inflammatory disorders, and inter stitial lung disease. It has been appreciated, however, that mild to moderate changes in scan activity, when these disorders are followed over time, are less than optimal. SPECT (single-photon emission computed tomography) scanning is a new technique designed to obviate this problem. SPECT scanning utilizes com puter acquisition to provide three-dimensional scanning and the additional ben efit of colorization to aid in discerning differences of uptake. SPECT scanning was performed on 22 patients with interstitial lung disease of various etiologies. Additionally, 7 patients had follow-up SPECT scanning to determine their re sponse to treatment. Two patients are presented as examples.

Angiology, Vol. 41, No. 12, 1023-1028 (1990)
DOI: 10.1177/000331979004101201
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