This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Kounis, N. G. Articles by Kitrou, M. P. Search for Related Content PubMed PubMed Citation Articles by Kounis, N. G. Articles by Kitrou, M. P. Social Bookmarking                         What's this?

Effects of Nitroglycerin on Myocardial Excursions and Velocities in the Early Hours of Acute Myocardial Infarction

Department of Medicine, University of Patras Medical School, Patras, Greece, Department of Cardiology Royal Victoria Hospital Belfast, Belfast, Northern Ireland

George M. Zavras

Department of Medicine, University of Patras Medical School, Patras, Greece, Department of Cardiology Royal Victoria Hospital Belfast, Belfast, Northern Ireland

Paraskevi J. Papadaki

Department of Medicine, University of Patras Medical School, Patras, Greece, Department of Cardiology Royal Victoria Hospital Belfast, Belfast, Northern Ireland

George D. Soufras

Department of Medicine, University of Patras Medical School, Patras, Greece, Department of Cardiology Royal Victoria Hospital Belfast, Belfast, Northern Ireland

Michael P. Kitrou

Department of Medicine, University of Patras Medical School, Patras, Greece, Department of Cardiology Royal Victoria Hospital Belfast, Belfast, Northern Ireland

The effects of sublingual nitroglycerin on septal and left ventricular wall motion were determined by echocardiography in the early hours of acute myocar dial infarction (MI) in 20 patients admitted via a mobile coronary care unit. Left ventricular and septal echoes were obtained in 11 patients with acute anterior MI and in 9 with acute inferior MI before and after administration of 500 µg sublingual nitroglycerin. In the group with acute anterior MI, nitroglyce rin did not significantly affect the B-C excursion, posterior wall excursion, and mean posterior wall velocity. Nitroglycerin significantly increased (P < 0.01), however, the systolic septal excursion, systolic septal velocity, diastolic septal excursion, and diastolic septal velocity. In the group with acute inferior MI, nitroglycerin significantly increased the B-C excursion (P < 0.01); posterior wall excursion (P < 0.01); mean posterior wall velocity (P < 0.01); systolic septal excursion (P < 0.01); diastolic septal excursion (P < 0.05), and diastolic septal velocity (P = 0.01) but did not affect the systolic septal velocity. All measure ments were obtained by use of a method of labeling and describing specific points of the wall motion that has been described recently.

Angiology, Vol. 40, No. 9, 783-790 (1989)
DOI: 10.1177/000331978904000902


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?