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Variability and Reproducibility of Transcutaneous Oxygen Tension Measurements in the Assessment of Peripheral Vascular Disease

Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota

P.J. Osmundson

Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota

Transcutaneous oxygen tension (TcPO₂) was measured according to a standard protocol in 43 limbs from 23 subjects, by use of oxygen-sensing electrodes attached to the chest (at a single site) or dorsum of the foot (at proximal and distal sites, located 1-2 cm apart). With the subjects supine, distal foot TcPO ₂ differed from proximal by an average of ±7.4 mmHg, and in 80% of all limbs the differences were between -6 mmHg and + 15 mmHg. The two TcPO ₂'s were subsequently combined to yield a single "average" value for each foot. TcPO₂ measurements were repeated twenty-four to forty-eight hours later; in the supine position the change in "average" foot TCPO ₂ from the first to second measurement was ±6.9 mmHg, and in 80% of limbs the changes were between -11 mmHg and +9 mmHg. Similar reproducibility data were also obtained for ankle/brachial blood pressure indices (ABIs), chest TcPO₂, and foot TcPO₂ during three minutes of leg elevation at 30 degrees. The authors conclude that: (1) TcPO₂ measurements from adjacent areas on the dorsum of the foot usually differ by 20-25% or less and (2) the short-term reproducibility of TcPO₂ between studies is comparable to that for ABIS.

Angiology, Vol. 40, No. 8, 695-700 (1989)
DOI: 10.1177/000331978904000802


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