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Angiology
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Favorable Effects of Prostacyclin Infusion in a Patient Given a Renal Transplant and with Severe Vascular Disease Secondary to Diabetes—A Case Report

Pier Luigi Bedani

Division of Nephrology, S. Anna Hospital, Ferrara, Italy

Orazio Fiocchi

Division of Nephrology, S. Anna Hospital, Ferrara, Italy

Silvia Soffritti

Division of Nephrology, S. Anna Hospital, Ferrara, Italy

Alberto Farinelli

Division of Nephrology, S. Anna Hospital, Ferrara, Italy

Microangiopathy is one of the most frequent diseases in diabetic patients. A diabetic man with a kidney transplant and with severe and progressive vasculo pathy with early necrosis of the fingers and toes was submitted to three prosta cyclin (PGI2) intravenous infusions (5 ng/kg/min for forty-eight hours) during a period of two months. Three months after the last infusion, radiographs of the hands and feet showed a marked reduction in the extent of the vascular calcifi cations and healing of the ischemic-necrotic areas. The authors discuss the im mediate and later effects of PGI2 infusion in a case of diabetic vascular disease.

Angiology, Vol. 40, No. 6, 589-592 (1989)
DOI: 10.1177/000331978904000612
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