SAGE Journals Online
Advertisement
Sign In to gain access to subscriptions and/or personal tools.

 

Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Advertisement

Sign In to gain access to subscriptions and/or personal tools.
Angiology
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Wollersheim, H.
Right arrow Articles by Lenders, J.W.M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Wollersheim, H.
Right arrow Articles by Lenders, J.W.M.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

Ephedrine Improves Microcirculation in the Diabetic Neuropathic Foot

H. Wollersheim

Department of Medicine, Division of General Internal Medicine, St. Radboud University Hospital, Nijmegen, The Netherlands

P.M. Netten

Department of Medicine, Division of General Internal Medicine, St. Radboud University Hospital, Nijmegen, The Netherlands

J.A. Lutterman

Department of Medicine, Division of General Internal Medicine, St. Radboud University Hospital, Nijmegen, The Netherlands

J.W.M. Lenders

Department of Medicine, Division of General Internal Medicine, St. Radboud University Hospital, Nijmegen, The Netherlands

A diabetic patient is described who developed one-sided neuropathic ulcera tion. Noninvasive microvascular measurements during distant cooling and in spiratory gasp revealed signs of sympathetic denervation. The initially elevated total skin blood flow measured by laser Doppler equipment and decreased capil lary perfusion as determined by transcutaneous oxygen tension measurements were both partially restored after treatment with the {alpha}1-sympathicomimetic ephedrine. The improvement occurred once more after rechallenge.

In conclusion this study further supports the hypothesis of a capillary steal phenomenon caused by extreme vasodilation within sympathetically denervated arteriovenous shunt vessels.

Angiology, Vol. 40, No. 12, 1030-1034 (1989)
DOI: 10.1177/000331978904001202
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?




Advertisement